LACC1 polymorphisms in inflammatory bowel disease and juvenile idiopathic arthritis.
Assadi G, Saleh R, Hadizadeh F, Vesterlund L, Bonfiglio F, Halfvarson J, Torkvist L, Eriksson AS, Harris HE, Sundberg E, D'Amato M.
Genes And Immunity. 2016; 17: 261-264. FI: 2,524 (Q2).
Functional Analyses of the Crohn’s Disease Risk Gene LACC1.
Assadi G, Vesterlund L, Bonfiglio F, Mazzurana L, Cordeddu L, Schepis D, Mjösberg J, Ruhrmann S, Fabbri A, Vukojevic V, Percipalle P, Salomons FA, Laurencikiene J, Törkvist L, Halfvarson J, D'Amato M. F
Plos One. 2016; 11: -. FI: 2,806 (Q1).
Inherited determinants of Crohn’s disease and ulcerative colitis phenotypes: a genetic association study.
Cleynen I, Boucher G, Jostins L, Schumm LP, Zeissig S, Ahmad T, Andersen V, Andrews JM, Annese V, Brand S, Brant SR, Cho JH, Daly MJ, Dubinsky M, Duerr RH, Ferguson LR, Franke A, Gearry RB, Goyette P, Hakonarson H, Halfvarson J, Hov JR, Huang H, Kennedy NA, Kupcinskas L, Lawrance IC, Lee JC, Satsangi J, Schreiber S, Théâtre E, van der Meulen-de Jong AE, Weersma RK, Wilson DC, International Inflammatory Bowel Disease Genetics Consortium, Parkes M, Vermeire S, Rioux JD, Mansfield J, Silverberg MS, Radford-Smith G, McGovern DP, Barrett JC, Lees CW.
Lancet. 2016; 387: 156-167. FI: 47,831 (Q1).
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
Ellinghaus D, Jostins L, Spain SL, Cortes A, Bethune J, Han B, Park YR, Raychaudhuri S, Pouget JG, Huebenthal M, Folseraas T, Wang Y, Esko T, Metspalu A, Westra HJ, Franke L, Pers TH, Weersma RK, Collij V, D'Amato M, Halfvarson J, Jensen AB, Lieb W, Degenhardt F, Forstner AJ, Hofmann A, Schreiber S, Mrowietz U, Juran BD, Lazaridis KN, Brunak S, Dale AM, Trembath RC, Weidinger S, Weichenthal M, Ellinghaus E, Elder JT, Barker, NWN, Andreassen OA, McGovern DP, Karlsen TH, Barrett JC, Parkes M, Brown MA, Franke A, IIBDGC, IGAS, IPSCSG, GAPC, PAGE.
Nature Genetics. 2016; 48: 510-510. FI: 27,959 (Q1).
Pathway-based Genome-wide Association Studies Reveal the Association Between Growth Factor Activity and Inflammatory Bowel Disease.
Li J, Wei Z, Chang X, Cardinale CJ, Kim CE, Baldassano RN, Hakonarson H.
Inflammatory Bowel Diseases. 2016; 22: 1540-1551. FI: 4,525 (Q1).
HLA Associations Distinguish Collagenous From Lymphocytic Colitis.
Westerlind H, Bonfiglio F, Mellander MR, Huebenthal M, Brynedal B, Bjork J, Torkvist L, Padyukov L, Ohlsson B, Lofberg R, Hultcrantz R, Franke A, Bresso F, D'Amato M.
American Journal Of Gastroenterology. 2016; 111: 1211-1213. FI: 9,566 (Q1).
A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn’s Disease and Human Gut Microbiome Composition.
Li D, Achkar JP, Haritunians T, Jacobs JP, Hui KY, D'Amato M, Brand S, Radford-Smith G, Halfvarson J, Niess, Jan-Hendrik, Kugathasan S, Buening C, Schumm LP, Klei L, Ananthakrishnan A, Aumais G, Baidoo L, Dubinsky M, Fiocchi C, Glas J, Milgrom R, Proctor D, Regueiro M, Simms LA, Stempak JM, Targan SR, Torkvist L, Sharma Y, Devlin B, Borneman J, Hakon X, Ramnik J, Daly M, Brant S, Rioux JD, Silverberg MS, Cho JH, Braun J, McGovern PB, Duerr RH.
Gastroenterology. 2016; 151: 724-732. FI: 18,392 (Q1).
A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.
Rivas MA, Graham D, Sulem P, Stevens C, Desch AN, Goyette P, Gudbjartsson D, Ingileif T, Unnur D, Frauke M, Soeren K, Mitja I, Li D, D'Amato M, Annese V, Vermeire S, Weersma RK., Halfvarson J, Paavola-Sakki P, Lappalainen M, Lek M, Cummings B, Tukiainen T, Haritunians T, Halme L, Koskinen LL, Ananthakrishnan AN, Luo Y, Heap GA, Visschedijk MC, MacArthur DG, Neale BM, Ahmad T, Anderson CA, Brant SR, Duerr RH, Silverberg MS, Cho JH, Palotie A, Saavalainen P, Kontula K, Farkkila M, Dermot PB, Franke A, Stefansson K, Rioux JD, Ramnik J, Daly MJ, UK IBD Genetics Consortium, NIDDK IBD Genetics Consortium.
Nature Communications. 2016; 7: 12342-12342. FI: 12,124 (Q1).
C13orf31 (FAMIN) is a central regulator of immunometabolic function.
Cader MZ, Boroviak K, Zhang Q, Assadi G, Kempster SL, Sewell GW, Saveljeva S, Ashcroft JW, Clare S, Mukhopadhyay S, Brown KP, Tschurtschenthaler M, Raine T, Doe B, Chilvers ER, Griffin JL, Kaneider NC, Floto RA, D'Amato M, Bradley A, Wakelam MJ, Dougan G, Kaser A.
Nat Immunol. 2016; 17: 1046-1056. FI: 21,506 (Q1).
Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.
Wang J, Thingholm LB, Skieceviciene J, Rausch P, Kummen M, Hov JR, Degenhardt F, Heinsen FA, Rühlemann MC, Szymczak S, Holm K, Esko T, Sun J, Pricop-Jeckstadt M, Al-Dury S, Bohov P, Bethune J, Sommer F, Ellinghaus D, Berge RK, Hübenthal M, Koch M, Schwarz K, Rimbach G, Hübbe P, Pan WH, Sheibani-Tezerji R, Häsler R, Rosenstiel P, D'Amato M, Cloppenborg-Schmidt K, Künzel S, Laudes M, Marschall HU, Lieb W, Nöthlings U, Karlsen TH, Baines JF, Franke A.
Nature Genetics. 2016; 48: 1396-1406. FI: 27,959 (Q1).
Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease.
Ventham NT, Kennedy NA, Adams AT, Kalla R, Heath S, O'Leary KR, Drummond H, IBD BIOM consortium, IBD CHARACTER consortium, Wilson DC, Gut IG, Nimmo ER, Satsangi J.
Nature Communications. 2016; 7: 13507-13507. FI: 12,124 (Q1).
Genetics of irritable bowel syndrome.
Henström M, D'Amato M.
Molecular And Cellular Pediatrics. 2016; 3: 7-7.
Increased serum levels of lipopolysaccharide and anti-flagellin antibodies in patients with diarrhea-predominant irritable bowel syndrome.
Dlugosz A, Nowak P, D’Amato M, Kermani GM, Nystrom J, Abdurahman S, Lindberg G.
Neurogastroenterol Motil. 2015; 27: 1747-54. FI: 3.310 (Q2).
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
Liu JZ, van Sommeren S, Huang H, Ng SC, Alberts R, Takahashi A, Ripke S Lee J, Shah T, Abedian S, Cheon JH, Cho J, Dayani NE, Franke L, Fuyuno Y, Hart A Juyal R, Juyal G, Kim WH, Morris AP, Poustchi H, Newman WG, Midha V, Orchard T, Vahedi H, Sood A, Sung JY, Malekzadeh R, Westra HJ, Yamazaki K, Yang SK, The International Multiple Sclerosis Genetics Consortium, The International IBD Genetics Consortium, Barrett JC, Alizadeh BZ, Parkes M, Thelma BK, Daly MJ, Kubo M, Anderson CA, Weersma RK.
Nat Genet. 2015; 47: 979-86. FI: 31.616 (Q1).
